Traditional bulk assays mask cellular heterogeneity and miss rare, high-value functional cells. Xdrop encapsulates individual cells in stable microfluidic double-emulsion droplets, enabling functional screening using standard flow cytometers and sorters. Detect secretion, interactions and cytotoxicity at true single-cell resolution while preserving cell viability.
Bulk assays hide individual cellular function. Rare, high-performing cells are easily missed, and functional behaviour cannot be reliably linked to specific cells. Xdrop overcomes these limitations by encapsulating single cells into double-emulsion droplets compatible with standard flow cytometers and sorters. Measure secretion, interactions, signalling, and cytotoxicity at true single-cell resolution — then recover the cells that matter.
Xdrop technology specializes in double emulsion droplet generation. These droplets are dispersed in an aqueous phase, ensuring compatibility with flow cytometers and flow sorters. This significantly broadens the range of assays achievable, enabling the analysis of secreted antibodies, cytokines, and other proteins, all confined within the droplets. It also facilitates the analysis of cell-cell interactions and cell killing assays, empowering the field of immunotherapy
The Xdrop platform combined with new capability of the MA900 Cell Sorter enables an integrated workflow for isolation of double-emulsion droplets with high efficiency and exceptional recovery rates. They can be used together to support high-throughput studies in immunotherapy, antibody discovery, and cellular research. Discover more in this application brochure.
Contact our dedicated support team, which includes field application scientists, cell biologists, and microfludics experts, to discuss your workflow needs. They can help you plan your experiments, from deciding on the best media and fluorophores to discussing downstream analyses.
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