Find Samplix' scientific papers and posters.
2024
T-DNA characterization of genetically modified 3-R-gene late blight-resistant potato events with a novel procedure utilizing the Samplix Xdrop® enrichment technology
Zarka, K. A., Jagd, L. M. & Douches, D. S.
Front Plant Sci 15, (2024); DOI: 10.3389/fpls.2024.1330429
2023
Droplet-based whole genome amplification: a novel approach for sequencing minute amounts of Mycobacterium tuberculosis DNA
Anzaan Dippenaar, Nabila Ismail, Tim H Heupink et al.
November 2023, PREPRINT available at Research Square; DOI: 10.21203/rs.3.rs-3655355
Long-read whole genome analysis of human single cells
Hård, J., Mold, J.E., Eisfeldt, J. et al.
Nat Commun 14, 5164 (2023). DOI: 10.1038/s41467-023-40898-3
A cis-regulatory point mutation at a R2R3-Myb transcription factor contributes to speciation by reinforcement in Phlox drummondii
Austin G. Garner, Andrew Cameron, Andrea E. Berardi, Robin Hopkins
bioRxiv 2023.04.19.537550; DOI: 10.1101/2023.04.19.537550
Skewed X-chromosome inactivation in unsolved neurodevelopmental disease cases can guide re-evaluation for X-linked genes
Giovenino, C., Trajkova, S., Pavinato, L. et al.
Eur J Hum Genet (2023). DOI: 10.21203/rs.3.rs-2179710/v1
2022
Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 components
Honglin Chen, Steffen Durinck, Hetal Patel, Oded Foreman, Kathryn Mesh, Jeffrey Eastham, Roger Caothien, Robert J Newman, Merone Roose-Girma, Spyros Darmanis, Soren Warming, Annalisa Lattanzi, Yuxin Liang, Benjamin Haley
Mol. Ther. Methods Clin. Dev. (2022). DOI: 10.1016/j.omtm.2022.10.016.
Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells
Keyi Geng, Lara G Merino, Linda Wedemann, Aniek Martens, Małgorzata Sobota, Yerma P Sanchez, Jonas Nørskov Søndergaard, Robert J White, Claudia Kutter
Genome Res. 2022. 32(10): 1876–1891; DOI: 10.1101/gr.276901.122
2021
Characterization of FMR1 repeat expansion and intragenic variants by indirect sequence capture
Valentina Grosso, Luca Marcolungo, Simone Maestri, Massimiliano Alfano, Denise Lavezzari, Barbara Iadarola, Alessandro Salviati, Barbara Mariotti, Annalisa Botta, Maria Rosaria D'Apice, Giuseppe Novelli, Massimo Delledonne, Marzia Rossato
Front. Genet. 2021. 12: 743230; DOIi: 10.3389/fgene.2021.743230
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, et al.
iScience. 2021. 24(12): 103463; DOI: 10.1016/j.isci.2021.103463
CRISPR/Cas9 deletions induce adverse on-target genomic effects leading to functional DNA in human cells
Keyi Geng, Lara Garcia Merino, Linda Wedemann, Aniek Martens, Malgorzata Sobota, Jonas Norskov Sondergaard, Robert J. White, Claudia Kutter
bioRxiv 2021.07.01.450727; DOI: 10.1101/2021.07.01.450727
Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Xiongwen Cao, Alexandra Khitun, Yang Luo, Zhenkun Na, Thitima Phoodokmai, Khomkrit Sappakhaw, Elizabeth Olatunji, Chayasith Uttamapinant, Sarah A. Slavoff.
Nat Commun 12, 508, 2021. DOI: 10.1038/s41467-020-20841-6
Verification of CRISPR editing and finding transgenic inserts by Xdrop Indirect sequence capture followed by short- and long- read sequencing
Blondal Thorarinn, Gamba Cristina, Jagd Lea Møller, Su Ling, Demirov Dimiter, Guo Shuang, Camille M. Johnston, Eva M. Riising, Wu Xiaolin, Marie J. Mikkelsen, Szabova Ludmila, Mouritzen Peter
Methods. 2021 Jul;191:68-77. DOI: 10.1016/j.ymeth.2021.02.003.
2020
Reconstruction of the birth of a male sex chromosome present in Atlantic herring
Rafati N, Chen J, Herpin A, Pettersson ME, Han F, Feng C, Wallerman O, Rubin CJ, Péron S, Cocco A, Larsson M, Trötschel C, Poetsch A, Korsching K, Bönigk W, Körschen HG, Berg F, Folkvord A, Kaupp UB, Schartl M, Andersson L.
Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24359-24368. DOI: 10.1073/pnas.2009925117
Xdrop: Targeted sequencing of long DNA molecules from low input samples using droplet sorting
Madsen EB, Höijer I, Kvist T, Ameur A, Mikkelsen MJ.
Hum Mutat. 2020 Sep;41(9):1671-1679. DOI: 10.1002/humu.24063.
Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55]
Schmid B, Prehn KR, Nimsanor N, Garcia BIA, Poulsen U, Jørring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Ramakrishna S, Muddashetty R, Steeg R, Bruce K, Mackintosh P, Ebneth A, Holst B, Cabrera-Socorro A.
Stem Cell Res. 2020 Sep 21;48:102005. doi: 10.1016/j.scr.2020.102005. Epub ahead of print. Erratum for: Stem Cell Res. 2019 Jan;34:101349. PMID: 32971461.
Identifying and isolating single immune cells based on their function using an Xdrop workflow
Supporting engineered cell therapy: targeted and accurate assessments of gene editing outcomes with Xdrop
Unbiased Amplification of single molecules enables even coverage of chromosomal DNA
Microfluidics based, long fragment, targeted enrichment with Xdrop
Transform discovery workflows. Effortlessly encapsulate single-cell libraries, enhancing the speed of your screening campaigns.
Elevate cell line development workflow. Encapsulate and screen single mammalian cells for enhanced antibody production.
Explore immune cell function in single-cell format assays, including cytokine, granzyme B, and cell killing assays.
Discover the Xdrop workflow, for CRISPR editing, CAR cassette insertion site validation, and more.
